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Linda F Thompson Selected Research

5'-Nucleotidase (5' Nucleotidase)

1/2016Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung Fibrosis.
5/2012Deficiency of CD73/ecto-5'-nucleotidase in mice enhances acute graft-versus-host disease.
10/2011Ecto-5'-nucleotidase (CD73) decreases mortality and organ injury in sepsis.
3/2010CD73 on tumor cells impairs antitumor T-cell responses: a novel mechanism of tumor-induced immune suppression.
3/2007Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors.
3/2007Protective role of ecto-5'-nucleotidase (CD73) in renal ischemia.
4/2006Ecto-5'-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury.
12/2004Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism.
12/2004Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia.
10/2002Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia.

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Linda F Thompson Research Topics

Disease

9Neoplasms (Cancer)
01/2021 - 02/2005
6Inflammation (Inflammations)
05/2012 - 01/2004
5Hypoxia (Hypoxemia)
02/2008 - 10/2002
3Fibrosis (Cirrhosis)
01/2017 - 04/2006
3Systemic Lupus Erythematosus (Libman-Sacks Disease)
07/2014 - 10/2009
3Human Influenza (Influenza)
12/2011 - 08/2011
2Breast Neoplasms (Breast Cancer)
01/2021 - 02/2005
2Pneumonia (Pneumonitis)
01/2017 - 04/2006
2Graft vs Host Disease (Graft-Versus-Host Disease)
01/2013 - 05/2012
2Lung Injury
10/2011 - 04/2006
2Severe combined immunodeficiency due to adenosine deaminase deficiency
06/2008 - 08/2002
1Corneal Injuries
07/2020
1Brain Neoplasms (Brain Tumor)
01/2019
1Glioblastoma (Glioblastoma Multiforme)
01/2019
1Neoplasm Metastasis (Metastasis)
01/2014
1Hematologic Neoplasms (Hematological Malignancy)
01/2013
1Sepsis (Septicemia)
10/2011
1Infections
10/2011
1Acute Lung Injury
01/2011
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
07/2008
1Multiple Sclerosis
07/2008
1Infarction (Infarctions)
03/2007
1Myocardial Ischemia (Ischemic Heart Diseases)
03/2007
1Ischemia
03/2007

Drug/Important Bio-Agent (IBA)

16Adenosine (Adenocard)FDA LinkGeneric
01/2019 - 12/2004
105'-Nucleotidase (5' Nucleotidase)IBA
01/2016 - 10/2002
6Purinergic P1 Receptors (Adenosine Receptor)IBA
01/2019 - 01/2004
4Adenosine Triphosphate (ATP)IBA
05/2012 - 10/2002
3Adenosine Monophosphate (AMP)IBA
03/2010 - 10/2002
3Oxygen (Dioxygen)IBA
02/2008 - 10/2002
2Proteins (Proteins, Gene)FDA Link
01/2021 - 09/2006
2Adenosine DeaminaseIBA
01/2016 - 09/2006
2AntibodiesIBA
01/2016 - 10/2009
2CytokinesIBA
07/2014 - 10/2011
2Adenine NucleotidesIBA
12/2004 - 10/2002
2Adenosine Diphosphate (ADP)IBA
12/2004 - 10/2002
1Immune Checkpoint InhibitorsIBA
01/2021
1Annexin A5IBA
01/2021
1Carbon Nanotubes (Carbon Nanotube)IBA
01/2021
1SS-A antibodiesIBA
07/2020
1EnzymesIBA
01/2019
1Hyaluronic Acid (Hyaluronan)IBA
01/2017
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
07/2014
1Purinergic P1 Receptor AntagonistsIBA
01/2014
1B-Cell Activating FactorIBA
12/2011
1InterferonsIBA
12/2011
1AutoantibodiesIBA
12/2011
1hydroxide ionIBA
12/2011
125-hydroxyvitamin DIBA
12/2011
1Peroxidase (Myeloperoxidase)IBA
10/2011
1Subunit VaccinesIBA
10/2011
1Neuraminidase (Sialidase)IBA
10/2011
1VaccinesIBA
10/2011
1Prednisone (Sone)FDA LinkGeneric
08/2011
1beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA
01/2011
1AllergensIBA
01/2011
1EndotoxinsIBA
01/2011
1Viral ProteinsIBA
10/2009
1Surface Antigens (Surface Antigen)IBA
10/2009
1deoxyribonucleoside kinasesIBA
06/2008
1Small Interfering RNA (siRNA)IBA
02/2008
1acetamideIBA
02/2008
11-propyl-8-(4-sulfophenyl)xanthineIBA
02/2008
1CarrageenanIBA
05/2007
1Messenger RNA (mRNA)IBA
09/2006
1Pentostatin (Nipent)FDA LinkGeneric
09/2006
1Bleomycin (Blenoxane)FDA LinkGeneric
04/2006
1indium-bleomycinIBA
04/2006
1nucleotidaseIBA
04/2006
1Biological ProductsIBA
02/2005
1ORALIT (ORS)IBA
02/2005
1NucleotidesIBA
12/2004
1Purinergic P1 Receptor AgonistsIBA
12/2004
14-O-carboxymethylascochlorinIBA
10/2002
1LuciferasesIBA
10/2002
1Antisense OligonucleotidesIBA
10/2002
1alpha,beta-methyleneadenosine 5'-diphosphateIBA
10/2002
1Cytochromes c (Cytochrome c)IBA
08/2002

Therapy/Procedure

4Therapeutics
01/2019 - 03/2007
2Immunotherapy
06/2011 - 03/2010
1Photothermal Therapy
01/2021
1Radiotherapy
01/2017
1Stem Cell Transplantation
01/2013
1Ligation
10/2011
1Punctures
10/2011
1Subcutaneous Injections
05/2007